GUMMY DROP TAHITI LEVEL 115 TRIAL

Both CQR-300 and CORE also brought about significant reductions in weight, body fat, total cholesterol, LDL-cholesterol, triglycerides, and fasting blood glucose levels over the respective study periods. They also acted as in vivo antioxidants, bringing about significant (p < 0.001) reductions in plasma TBARS and carbonyls. RESULTS: CQR-300 as well as CORE exhibited antioxidant properties in vitro.

Anthropometric measurements and blood sampling were done at the beginning and end of the study period. All participants received two daily doses of CQR-300, CORE, or placebo and were encouraged to maintain their normal levels of physical activity. METHODS: The first part of the study investigated the in vitro antioxidant properties of CQR-300 and CORE using 3 different methods, while the second part of the study was a double-blind placebo controlled design, involving initially 168 overweight and obese persons (38.7% males 61.3% females ages 19-54), of whom 153 completed the study. The aim of this study was to compare the effect of a proprietary extract of Cissus quadrangularis (CQR-300) to that of a proprietary formulation containing CQR-300 (CORE) on weight, blood lipids, and oxidative stress in overweight and obese people. Obesity is generally linked to complications in lipid metabolism and oxidative stress. Laboratory of Nutrition and Nutritional Biochemistry, Department of Biochemistry, University of Yaoundé I, Yaoundé, Cameroon.

Oben JE, Enyegue DM, Fomekong GI, Soukontoua YB, Agbor GA. The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress. This is the first reported occurrence of iridoids in C. The structures were elucidated by analysis of their spectroscopic data and by direct comparison with literature. The compounds 3 and 7 are first reported from this plant. Two new iridoids 6-O-trans-cinnamoyl catalpol (1) and 6-O-meta-methoxy-benzoyl catalpol (2) along with a known iridoid picroside 1 (3), two stilbenes quadrangularin A (4) and pallidol (5), quercitin (6), quercitrin (7), beta-sitosterol (8) and beta-sitosterol glycoside (9) were isolated from Cissus quadrangularis Linn. Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow, India. This apparently synergistic formulation should prove helpful in the management of obesity and its related complications. CONCLUSION: Although the Cissus quadrangularis-only group showed significant reductions on all variables compared to the placebo group, the Cissus quadrangularis/Irvingia gabonensis combination resulted in even larger reductions.

GUMMY DROP TAHITI LEVEL 115 TRIAL

The magnitude of the differences was noticeable by week 4 and continued to increase over the trial period.

RESULTS: Compared to the placebo group, the two active groups showed a statistically significant difference on all six variables by week 10. A total of six anthropomorphic and serological measurements (body weight, body fat, waist size total plasma cholesterol, LDL cholesterol, fasting blood glucose level) were taken at baseline and at 4, 8 and 10 weeks. Capsules containing the placebo or active formulations were administered twice daily before meals no major dietary changes nor exercises were suggested during the study. The participants were randomly divided into three equal (n = 24) groups: placebo, Cissus quadrangularis-only, and Cissus quadrangularis/Irvingia gabonensis combination. METHODS: The study was a 10 week randomized, double-blind, placebo-controlled design involving 72 obese or overweight participants (45.8% male 54.2% female ages 21-44 mean age = 29.3). To evaluate the effects of two formulations, Cissus quadrangularis-only and a Cissus quadrangularis/Irvingia gabonensis combination, on weight loss in overweight and obese human subjects. Laboratory of Nutrition and Nutritional Biochemistry, Department of Biochemistry, B,P, 812, University of Yaoundé 1, Yaoundé, Cameroon.

Oben JE, Ngondi JL, Momo CN, Agbor GA, Sobgui CS. The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study.

Gummy drop tahiti level 115